Primary Care Without the One-Size-Fits-All Approach

Every patient brings a different history, lifestyle, set of concerns, and healthcare goals into the exam room.
First City Clinic provides individualized care designed around the person—not simply the diagnosis.
Our services include routine primary care, acute illness evaluation, chronic disease management, preventive healthcare, gender-affirming hormone therapy, PrEP and PEP, HIV/STI testing, and treatment.
By offering many essential healthcare services through one practice, we aim to make it easier for patients to build an ongoing relationship with a provider who knows their health history and understands their needs.

Your Trusted Ally in Healthcare

At First City Clinic, located in Savannah, Georgia, we pride ourselves on providing comprehensive primary care tailored to adults, with a strong focus on creating an affirming environment for the local LGBTQ+ community. Our dedicated team understands the unique health needs of our patients and offers a range of services, including preventive care, chronic condition management, gender-affirming hormone therapy, and HIV/STI testing and treatment. We aim to ensure every patient feels respected and comfortable discussing their health, making us your trusted ally in navigating healthcare with compassion and clarity.

Jennifer Reno, M.D., Ph.D.

I earned my bachelor’s degree in Biological Sciences from Florida State University before completing the M.D./Ph.D. program at the University of Illinois, where I received both a master’s degree and Ph.D. in Microbiology, followed by my Doctor of Medicine. I completed my residency in Anatomic and Clinical Pathology at the University of Cincinnati Medical Center and a fellowship in Forensic Pathology through Augusta University and the Medical College of Georgia. I am board certified in both Anatomic Pathology and Clinical Pathology.  I have been involved in providing gender affirming care for as long as I have had a medical license

As a transgender physician, I bring both professional expertise and lived experience to my work. I am passionate about providing compassionate, affirming care and is excited to serve the Savannah community. Outside of medicine, I enjoy reading, attending the theater, and rowing.

Frequently Asked Questions

Your questions answered for clarity and assurance about our services.

What types of services do you offer?

We provide a range of services including preventive care, chronic condition management, gender-affirming hormone therapy, and HIV/STI testing and treatment.

Do you have LGBTQ+ affirming care?

Yes! We specialize in creating an affirming, respectful environment specifically for our local LGBTQ+ community.

How can I contact First City Clinic?

You can reach us at (912) 296-3744 or email jennifer.reno@firstcityclinic.com for any inquiries.

Where are you located?

We are based in Savannah, Georgia, providing accessible primary care to the local community.